Diatoms are the most species-rich microalgal class with estimated ≥ 100,000 species, and contribute to 20% of global carbon fixation and oxygen production. Secondary metabolites play diverse roles in microalgae-environment interaction. Main focus of our group is the functional study of secondary metabolism (metabolites) in diatoms under biotic and abiotic stress.

Curriculum Vitae Prof. Hui-Xi Zou

Publications

2023

30. Hui-Xi Zou, Tianli Sun, Bangqun Jin, Shengqin Wang (2023) sBGC-hm: an atlas of secondary metabolite biosynthetic gene clusters from the human gut microbiome, Bioinformatics, 39(3), btad131, DOI: 10.1093/bioinformatics/btad131

2022

29. Li-Li Chen, Yi-Cheng Xu, Yun Yang, Nan Li, Hui-Xi Zou, Hai-Hong Wen, Xiufeng Yan (2022) Prediction of peptide-induced silica formation under a wide pH range by molecular descriptors, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 653, 130030

DOI: 10.1016/j.colsurfa.2022.130030

28. Haiyan Lin, Jiayi Sun, Zhiwei Hu, Chenxi Cheng, Sue Lin, Hui-Xi Zou, Xiufeng Yan (2022) Variation in Glucosinolate Accumulation among Different Sprout and Seedling Stages of Broccoli (Brassica oleracea var. italica), Plants, 11(12), 1563, DOI: 10.3390/plants11121563

27. Peng Cao, Yuhui Fang, Zikui Zheng, Xia Han, Hui-Xi Zou, Xiufeng Yan (2022) Occurrence of Neopestalotiopsis clavispora Causing Leaf Spot on Dendrobium officinale in China, Plant Disease, 106: 1761

DOI: 10.1094/PDIS-11-21-2432-PDN

26. Peng Cao, Zikui Zheng, Yuhui Fang, Xia Han, Hui-Xi Zou, Xiufeng Yan (2022) First Report of Stem Rot Caused by Fusarium kyushuense on Dendrobium officinale in China, Plant Disease, 106: 2257

DOI: 10.1094/PDIS-12-21-2719-PDN

2021

25. Dong-Sheng Zhao, Zhi-Wei Hu, Ling-Li Dong, Xiao-Jie Wan, Shengqin Wang, Nan Li, Yao Wang, Shu-Ming Li, Hui-Xi Zou, Xiufeng Yan (2021) A Type III Polyketide Synthase (SfuPKS1) Isolated from the Edible Seaweed Sargassum fusiforme Exhibits Broad Substrate and Catalysis Specificity, Journal of Agricultural and Food Chemistry, 69(48): 14643-14649

DOI: 10.1021/acs.jafc.1c05868

2020

24. Peichao Chen, Ya Zhang, Man Xu, Hongjun Chen, Hui-Xi Zou, Xu Zhang, Haibin Tong, Cuiping You, Mingjiang Wu (2020) Proteomic landscape of liver tissue in old male mice that are long-term treated with polysaccharides from Sargassum fusiforme, Food & Function, 11: 3632-3644

DOI: 10.1039/D0FO00187B

23. Tao Liu, Yutong Cui, Xuli Jia, Binbin Chen, Zengling Ma, Hui-Xi Zou, Shengqin Wang, Mingjiang Wu (2020) The complete mitochondrial genome of brown algae: Sargassum fusiforme (Harvey) Setchell, Mitochondrial DNA Part B, 5(1): 830-831

DOI: 10.1080/23802359.2020.1715892

22. Tao Liu, Yutong Cui, Xuli Jia, Binbin Chen, Zengling Ma, Hui-Xi Zou, Shengqin Wang, Mingjiang Wu (2020) The complete chloroplast genome of Sargassum fusiforme, Mitochondrial DNA Part B, 5(1): 576-577

DOI: 10.1080/23802359.2019.1710296

21. Shengqin Wang, Lidong Lin, Yijian Shi, Weiguo Qian, Nan Li, Xiufeng Yan, Hui-Xi Zou, Mingjiang Wu (2020) First Draft Genome Assembly of the Seaweed Sargassum fusiforme, Frontiers in Genetics, 11: 590065

DOI: 10.3389/fgene.2020.590065

20. Hui-Xi Zou, Dongsheng Zhao, Haihong Wen, Nan Li, Weiguo Qian, Xiufeng Yan (2020) Salt stress induced differential metabolic responses in the sprouting tubers of Jerusalem artichoke (Helianthus tuberosus L.), PLoS ONE, 15(6): e0235415

DOI: 10.1371/journal.pone.0235415

19. Xiaoli Liang, Yinliang Yang, Chao Zou, Wei Chen, Hui-Xi Zou, Yun Yang (2020) Au decahedra with High yield for the improved synthesis of Au nanobipyramids, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 597: 124749

DOI: 10.1016/j.colsurfa.2020.124749

2019

18. Shengqin Wang, Zhihong Zheng, Hui-Xi Zou, Nan Li, Mingjiang Wu (2019) Characterization of the secondary metabolite biosynthetic gene clusters in archaea, Computatioanl Biology and Chemistry, 78: 165-169

DOI: 10.1016/j.compbiolchem.2018.11.019

17. Shengqin Wang, Na Li, Nan Li, Hui-Xi Zou, Mingjiang Wu (2019) A Comparative Analysis of Biosynthetic Gene Clusters in Lean and Obese Humans, BioMed Research International, 2019: 6361320

DOI: 10.1155/2019/6361320

16. Yonghua Zhang, Shengqin Wang, Weiguo Qian, Yijian Shi, Nan Li, Xiufeng Yan, Hui-Xi Zou, Mingjiang Wu (2019) Characterization of the complete chloroplast genome of Sargassum fusiforme and its phylogenomic position within phaeophyceae, Mitochondrial DNA Part B, 4(2): 3258-3259

DOI: 10.1080/23802359.2019.1671246

15. Shengqin Wang, Nan Li, Hui-Xi Zou, Mingjiang Wu (2019) Gut microbiome-based secondary metabolite biosynthetic gene clusters detection in Parkinson’s disease, Neuroscience Letters, 696: 93-98

DOI: 10.1016/j.neulet.2018.12.021

2017

14. Peng Zhang, Xiuna Wang, Aili Fan, Yanjing Zheng, Xingzhong Liu, Shihua Wang, Hui-Xi Zou, Berl R. Oakley, Nancy P. Keller, Wen-Bing Yin (2017) A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici, Molecular Microbiology, 105: 469-483

DOI: 10.1111/mmi.13711

13. Yanjing Zheng, Ke Ma, Haining Lyu, Ying Huang, Hongwei Liu, Ling Liu, Yongsheng Che, Xingzhong Liu, Hui-Xi Zou, Wen-Bing Yin (2017) Genetic Manipulation of the COP9 Signalosome Subunit PfCsnE Leads to the Discovery of Pestaloficins in Pestalotiopsis fici, Oganic letters, 19 (17): 4700-4703

DOI: 10.1021/acs.orglett.7b02346

12. Yanjing Zheng, Xiuna Wang, Xiaoling Zhang, Wei Li, Gang Liu, Shihua Wang, Xiufeng Yan, Hui-Xi Zou, Wen-Bing Yin (2017) COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici, Science China-Life Sciences, 60(6): 656-664

DOI: 10.1007/s11427-017-9068-4

2016

11. Peichao Chen, Dan He, Ya Zhang, Shanshan Yang, Liujun Chen, Shengqin Wang,  Hui-Xi Zou, Zhiyong Liao,  Xu Zhang, Mingjiang Wu (2016) Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging, Food & Function, 7: 4576-4588

DOI: 10.1039/C6FO00628K

10. Wei-Guo Qian, Nan Li, Li-Dong Lin, Tao Xu, Xu Zhang, Li-Hua Wang, Hui-Xi Zou, Ming-Jiang Wu, Xiu-Feng Yan (2016) Parallel analysis of proteins in brown seaweed Sargassum fusiforme responding to hyposalinity stress, Aquaculture, 465: 189-197

DOI: 10.1016/j.aquaculture.2016.08.032

2015

9. Carsten Wunsch, Hui-Xi Zou, Uwe Linne, Shu-Ming Li (2015) C7-prenylation of tryptophanyl and O-prenylation of tyrosyl residues in dipeptides by an Aspergillus terreus prenyltransferase, Applied Microbiology and Biotechnology, 99(4): 1719-1730

DOI: 10.1007/s00253-014-5999-6

8. Aiqin Zhang, Tao Xu, Huixi Zou, Qiuying Pang (2015) Comparative proteomic analysis provides insight into cadmium stress responses in brown algae Sargassum fusiforme, Aquatic Toxicology, 163: 1-15

DOI: 10.1016/j.aquatox.2015.03.018

7. Hui-Xi Zou, Qiu-Ying Pang, Ai-Qin Zhang, Li-Dong Lin, Nan Li, Xiu-Feng Yan (2015) Excess copper induced proteomic changes in the marine brown algae Sargassum fusiforme, Ecotoxicology and Environmental Safety, 111: 271-280

DOI: 10.1016/j.ecoenv.2014.10.028

2014

6. Hui-Xi Zou, Qiu-Ying Pang, Li-Dong Lin, Ai-Qin Zhang, Nan Li, Yan-Qing Lin, Lu-Min Li, Qin-Qin Wu, Xiu-Feng Yan (2014) Behavior of the Edible Seaweed Sargassum fusiforme to Copper Pollution: Short-Term Acclimation and Long-Term Adaptation, PLoS ONE, 9(7): e101960

DOI: 10.1371/journal.pone.0101960

5. Hui-Xi Zou, Nan Li, Li-Hua Wang, Ping Yu, Xiu-Feng Yan (2014) Equilibrium and Kinetic Studies of Cd2+ Biosorption by the Brown Algae Sargassum fusiforme, PLoS ONE, 9(4): e95242

DOI: 10.1371/journal.pone.0095242

2011

4. Hui-Xi Zou, Xiulan Xie, Xiao-Dong Zheng, Shu-Ming Li (2011) The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations, Applied Microbiology Biotechnology, 89: 1443-1451

DOI: 10.1007/s00253-010-2956-x

2010

3. Hui-Xi Zou, Xiu-Lan Xie, Uwe Linne, Xiao-Dong Zheng, Shu-Ming Li (2010) Simultaneous C7- and N1-prenylation of cyclo-L-Trp-L-Trp catalyzed by a prenyltransferase from Aspergillus oryzae, Organic & Biomolecular Chemistry, 8: 3037-3044

DOI: 10.1039/c002850a

2009

2. Hui-Xi Zou, Xiaodong Zheng, Shu-Ming Li (2009) Substrate Promiscuity of the Cyclic Dipeptide Prenyltransferases from Aspergillus fumigatus, Journal of Natural Products, 72: 44-52

DOI: 0.1021/np800501m

2008

1. Edyta Stec, Nicola Steffan, Anika Kremer, Hui-Xi Zou, Xiaodong Zheng, Shu-Ming Li (2008) Two Lysine Residues are Responsible for the Enzymatic Activities of Indole Prenyltransferases from Fungi, ChemBioChem, 9(13): 2055-2058

DOI: 10.1002/cbic.200800237